Prednisone mechanism of action

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Pharmacology of corticosteroids. Nov. 28, 2013. • 258 likes • 46,647 views. Health & Medicine Technology. Presentation for Medical undergraduates for teaching pharmacology. It deals with Physiology of steroid hormones and their action along with agents which are used therapeutically with their action, adverse effects and therapeutic uses. Mechanism of Action. Glucocorticoids have many mechanisms of action, including transactivation, transrepression, physicochemical effects on cell membranes, synchronization of cell division and tissue remodeling, cross-reaction with other steroid hormone receptors (mineralocorticoid receptor), and others. ... Prednisolone showed a dose-dependent. Mechanism of steroid action in inflammation: inhibition of prostaglandin synthesis and release Abstract Acute arthritis was induced by injection of cell-free extract of group A Streptococci into the knee joints of mature male rats.
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